Jecho Laboratories, Inc.
Jecho Laboratories, Inc. (Jecho Labs) is a privately owned biopharmaceutical company that researches and develops innovative therapeutic biologics, including therapeutic monoclonal antibodies, cytokines, immunotoxins, and vaccines to treat a broad range of diseases and cancers.
Jecho Labs’ headquarters and main facilities are in Frederick Maryland, USA, near the National Institute of Health (NIH).
Jecho Labs’ mission is to discover and develop biologics to combat the most severe human diseases, including cancers and Covid-19. We here at Jecho Labs wish to help improve human health by developing the most effective and innovative biological medicines.
New Project on Coronavirus
Jecho Biopharm/Jecho Labs are collaborating with Shanghai Jiao Tong University, People’s Hospital of Henan Province, and Wuhan Virology Institute (Chinese Academy of Sciences) on developing therapeutic neutralizing antibody against COVID-19.
Using our established and fully human scFv phage display library, we will screen antibodies with high affinity to S1 and S2 domains of the spike protein and evaluate their in vitro cell neutralizing potency through the cell based model system established in the lab. GMP production will be conducted by Jecho Biopharm to support clinical studies to serve the current urgent needs from the patients.
UPDATE March 23rd: Using our established fully human scFv phage display library, we have isolated dozens of monoclonal antibodies recognizing specifically the receptor binding domain (RBD) of the SARS-C0V-2 spike protein and are evaluating their in vitro virus neutralizing potency through the cell based model system established in the lab. GMP production will be conducted by Jecho Biopharm to support clinical studies to serve the current urgent needs from the patients.
Research and Development
Jecho Labs has an excellent research and development team, holding multiple patents, licenses, and propriety technologies. In addition to its collaboration with various U.S research institutions, Jecho Lab is a strategic partner with Shanghai Jiaotong University (SJTU) School of Pharmacy in China.
Jecho Labs R&D facility in Frederick has four major technical departments – Drug Discovery, Process Development (PD), Analytical Development (AD), and a Quality Unit (QA and QC). The technical team holds multiple patents, licenses, and proprietary technologies. The team possess a broad range of knowledge and experiences in biopharmaceutical development: molecular biology, immunology, virology, biochemistry, biochemical engineering, process development, clinical manufacturing at large scales, etc.
Jecho Labs assesses current market conditions for bio-similar and novel biopharmaceuticals, and the drug discovery process begins when a viable market is determined. Once optimized a drug, the Drug Discovery Group then hands it off to the Process Development Group to develop a scalable manufacturing process. The Analytical Development Group develops analytical methods to ensure the process robustness and drug safety and efficacy. The Quality Unit ensures regulatory compliance throughout the entire process.
Jecho Labs, in collaboration with domestic and overseas manufacturing partners, focuses on developing bio-therapeutic products and production processes, including novel drug candidates, bio-similars, and innovative bio-manufacturing technologies. Jecho Labs serves as an upstream partner to manufacturers, providing bio-similar and novel biopharmaceutical products and processes. Jecho Labs has entered a partnership with Jecho Biopharmaceuticals (Jecho Biopharma) in Tianjin, China. The products, including monoclonal antibodies, recombinant proteins, and vaccines, will be manufactured and marketed worldwide.
Frederick's Top 50 Workplace
"The business, just five years old, shares a clear vision with employees to engage them in its objectives and is working on a stock option that may be offered to staff."
New Pilot and Manufacturing Facility
Jecho is currently establishing a new multi-products pilot and clinical manufacturing facility.
In phase I, the planned site will include a 250-500L pilot scale line and four 3,000-5,000L production lines. Corresponding purification capacity will also be built on-site.
In phase II, additional six or more 5,000L production lines will be added. Optional 10,000 to 20,000 L production capacities will be installed as needed.
Partnership with Shanghai Jiao Tong University School of Pharmacy
Jecho Labs has entered a strategic partnership with Shanghai Jiao Tong University (SJTU) School of Pharmacy to develop novel biopharmaceutics.
Jecho will help bring SJTU’s scientific research discoveries into clinical studies. Jecho will provide guidance and assistance in license acquisition of early stage development therapeutic agents and new technologies. Additionally, Jecho will make its US R&D facility available for training SJTU technical staff.
Want to join us?
Jecho Labs has an excellent research and development team, holding multiple patents, licenses, and propriety technologies, and R&D facilities that include specialized labs for cell culture, bacterial fermentation, purification, physiochemical and biological analysis and are equipped with state-of-the-art process and analytical instruments.