Technology Platform

High-Performance VHH Phage Libraries

High-Performance VHH Phage Libraries – Key Features

  • Naïve Alpaca Immune Repertoire
    • Derived from a diverse and robust alpaca immune system to enhance target specificity.
  • Advanced Two-Point Shuffling
    • Utilizes two-point shuffling for superior diversity, leading to a high complexity of over 10¹¹ independent clones.
  • High Sequence Quality
    • Ensures over 90% of clones have correct sequences with minimal duplications, optimizing discovery efficiency.
  • Multi-Specific Adaptability
    • Designed for high adaptability, making it ideal for multi-specific antibody formats.
  • Proven Validation & Pipeline Contributions
    • Rigorously validated by identifying high-affinity and abundant binders against challenging targets.
    • Significant contributions to internal and partner pipelines, accelerating therapeutic innovation.

High-Performance scFv Fully Human Phage Libraries

High-Performance scFv Fully Human Phage Libraries – Key Features

  • Diverse Lymphoid Sources
    • Derived from B cells of PBMC, spleen, and lymph nodes to maximize immune repertoire diversity.
  • Flexible Structural Formats
    • VH-VL oriented scFv with a 3xG4S linker for enhanced stability.
    • VL-VH oriented scFv with a 6xG4S linker for optimized binding properties.
  • Exceptional Library Complexity
    • Over 10¹⁰ unique clones, ensuring broad target recognition and high-affinity binders.
  • Proven Performance & Validation
    • Successfully identified high-affinity binders against more than a dozen antigens.
    • Direct contributions to internal and partner pipelines, accelerating antibody discovery and therapeutic development.

Cell Line Development and Characterization

Cell Line Development and Characterization – Key Features

  • Stable Production Cell Line Generation
    • Streamlined cell line generation process to ensure high stability, high productivity, and full traceability.
    • Mammalian and bacterial cell lines.
  • Assay Cell Line Generation
    • Stable or transient transfection of mammalian cells.
    • Genetic engineering of host cell lines.